Clinical efficacy and safety of 6-thioguanine in the treatment of childhood acute lymphoblastic leukemia
نویسندگان
چکیده
منابع مشابه
Presenting Clinical and Laboratory Data of Childhood Acute Lymphoblastic Leukemia
Abstract Background Leukemia is the most prevalent childhood cancer and Acute Lymphoblastic Leukemia (ALL) constitutes 75% of all cases. The most frequent presenting symptoms are fever, weight loss and pallor. Early detection of clinical symptoms positively affects timely diagnosis. The objectives of the present study were to assess frequency of presenting symptoms, laboratory data, immune ph...
متن کاملpresenting clinical and laboratory data of childhood acute lymphoblastic leukemia
abstract background leukemia is the most prevalent childhood cancer and acute lymphoblastic leukemia (all) constitutes 75% of all cases. the most frequent presenting symptoms are fever, weight loss and pallor. early detection of clinical symptoms positively affects timely diagnosis. the objectives of the present study were to assess frequency of presenting symptoms, laboratory data, immune phen...
متن کاملAssocition between LAPTM4B gene polymorphism and the risk of childhood acute lymphoblastic leukemia
Introduction: Evidence suggests that Lysosome associated protein transmembrane 4B (LAPTM4B) contributes to the risk of numerous cancers. The present study aimed to find out the impact of LAPTM4B polymorphism on the risk of childhood acute lymphoblastic leukemia (ALL) in the southeastern Iranian population. Materials and Methods: A total of 230 subjects including 110 children diagnosed with ALL ...
متن کاملCharacterization of Immunophenotypic Aberrancies in Adult and Childhood Acute Lymphoblastic Leukemia: Lessons from Regional Variation
Background & Objective: Although the antigen expression patterns of acute lymphoblastic leukemia (ALL) are well known, this study attempted to evaluate commonly used immune markers for immunophenotyping of acute leukemia to set the minimum of necessary diagnostic panels by flow cytometry. Methods: This study evaluated 89 patients referred from all over th...
متن کاملThe role of ATP-binding cassette transporter A2 in childhood acute lymphoblastic leukemia multidrug resistance
Acute lymphoblastic leukemia (ALL) is one of the most prevalent hematologic malignancies in children. Although the cure rate of ALL has improved over the past decades, the most important reason for ALL treatment failure is multidrug resistance (MDR) phenomenon. The current study aims to explain the mechanisms involved in multidrug resistance of childhood ALL, and introduces ATP-binding cassette...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medicine
سال: 2020
ISSN: 0025-7974,1536-5964
DOI: 10.1097/md.0000000000020082